Research Centers for Barrett’s Esophagus Translational Research Network (BETRNet)(U54)

Funding Agency:
National Institutes of Health

This funding opportunity announcement (FOA) solicits applications for multi-institutional, trans-disciplinary, translational Research Centers to serve as the main units of the Barrett’s Esophagus Translational Research Network (BETRNet). The BETRNet is an NCI program established to address the rising incidence of esophageal adenocarcinoma in the United States and to energize this field of research. Specifically, the program seeks a better understanding of the biology of esophageal adenocarcinoma and its precursor lesion, Barrett’s esophagus, as the foundation for validated preventive measures that would improve patient management. BETRNet will encompass three to four Research Centers (to be supported by this FOA) and a single Coordinating Center (to be supported by a companion FOA, RFA-CA-16-007). The Research Centers' activities will be facilitated by the Coordinating Center in the following main areas: network interactions and collaborations, participation in the patient registry-virtual biorepository, and participation in cross-BETRNet pilot projects.  A goal of the patient registry-virtual biorepository is to function as a centralized shared resource for the entire program to advance research in this area.  

An applicant institution may submit more than one application in response to this FOA provided that these applications correspond to different investigator teams and different PDs/PIs.


  • Letter of Intent Due Date(s): April 23, 2016
  • Application Due Date(s): May 23, 2016

RFA-CA-16-006 Expiration Date May 24, 2016

Agency Website



Amount Description

Application budgets must reflect the actual needs of the proposed center but must not exceed $900,000 per year in direct costs.

The total project period for an application submitted in response to this FOA may not exceed 5 years. 

Funding Type





Medical - Basic Science
Medical - Clinical Science
Medical - Translational

External Deadline

May 23, 2016