Research Grants

Funding Agency:
Tuberous Sclerosis Alliance

The TS Alliance endeavors to stimulate, support and coordinate research that will lead to a cure for tuberous sclerosis complex (TSC) while improving the lives of those affected. Most TS Alliance research grants support small, focused projects that allow investigators to develop preliminary data to compete for funding from larger organizations such as the National Institutes of Health (NIH).  Other TS Alliance research grants support postdoctoral fellowships to encourage young investigators to engage in TSC research.  Many of these investigators will continue to pursue TSC research when they establish their own independent laboratories.

Researchers funded by the TS Alliance have a strong history of obtaining additional funding: between 1984 and 2019, principal investigators who received a total of $21.2 million from the TS Alliance subsequently garnered an additional $15.6 million from the Department of Defense’s Tuberous Sclerosis Complex Research Program and $326 million from the NIH.

Letters of Intent Due: April 6, 2020

Agency Website

Areas of Interest

Types of Grants

Postdoctoral Fellowships

  • Postdoctoral Fellowship awards may support any type of basic or translational research relevant to TSC that provides an outstanding opportunity for the trainee’s professional growth.
  • Postdoctoral Fellowship awards are intended to provide funding for an individual who has recently earned a PhD or MD degree and is working with a Sponsor to do research relevant to TSC.
  • The Sponsor must be tenure-track faculty or an equivalent level at a research institution or company. The award is intended to fund the applicant’s salary and some of the laboratory supplies or tools necessary to conduct the proposed research. The award is not intended to fund technical support for the project or to purchase equipment in the Sponsor’s laboratory. The trainee applicant is considered to be the “Principal Investigator” for the purpose of postdoctoral fellowship awards.

Research Grants

  • Research Grant proposals should address one of the following four high-priority areas:

    • Understanding phenotypic heterogeneity in TSC, i.e., research on genetic, biologic, or environmental factors that might explain why TSC is so different from person to person
    • Gaining a deeper knowledge of TSC signaling pathways and the cellular consequences of TSC deficiency
    • Improving TSC disease models, whether cell-based, tissue-based, or animal models
    • Developing clinical biomarkers or patient-reported outcome measures for TSC, particularly those that assess disease burden or stratify an individual’s risk of progression or developing specific manifestations of TSC
  • Research Grant awards are intended to provide funding for an independent researcher, whether tenure-track faculty, non-tenure-track faculty or staff, or an equivalent level at a research institution or company. The award may support laboratory supplies, personnel costs, services, or equipment necessary to conduct the proposed research.
  • The TS Alliance fully supports collaborative projects between co-investigators, but only one investigator may be considered the “Principal Investigator” for the purpose of applying through the online system.

Eligibility Requirements

This opportunity is open to all investigators at established academic or research institutions or at pharmaceutical or biotech companies worldwide.  Researchers residing in the U.S. do not need to be U.S. citizens to apply for funding.



Funding Type



Junior Faculty
Medical Fellow/Resident
Post Doctoral Fellows


Medical - Basic Science
Medical - Clinical Science
Medical - Translational

External Deadline

April 6, 2020