Research on the Health of Women of Understudied, Underrepresented and Underreported (U3) Populations – An ORWH FY19 Administrative Supplement (Admin Supp Clinical Trial Optional))

Funding Agency:
National Institutes of Health

The Office of Research on Women's Health (ORWH) announces the availability of administrative supplements to support interdisciplinary, transdisciplinary and multidisciplinary research focused on the effect of sex/gender influences at the intersection of several social determinants, including but not limited to: race/ethnicity, socioeconomic status, education, health literacy and other social determinants in human health and illness. This research includes preclinical, clinical, behavioral and translational studies with the specific purpose to provide Administrative Supplements to active NIH parent grants for one year to address health disparities among women of populations in the US who are understudied, underrepresented and underreported in biomedical research.

The proposed research must address an area specified within Goal 1 and 2 of the new Trans-NIH Strategic Plan for Women's Health Research "Advancing Science for the Health of Women". These goals focus on advancing rigorous research that is relevant to the health of women (Goal 1) and developing methods and leveraging data sources to consider sex and gender influences that enhance research for the health of women (Goal 2).

Projects must include a focus on one or more NIH-designated health disparities populations, which include Blacks/African Americans, Hispanics/Latinos, American Indians/Alaska Natives, Asian Americans, Native Hawaiians and other Pacific Islanders, socioeconomically disadvantaged populations, underserved rural populations, and sexual and gender minorities (SGM). Combinations of one or more populations is also encouraged, e.g. socioeconomically disadvantaged sexual and gender minorities.

Only one application per parent award may be submitted.
Application Due Date(s): April 8, 2019
PA-19-205 Expiration Date April 9, 2019

Agency Website

Eligibility Requirements

All organizations administering an eligible parent award may apply for a supplement under this announcement.

This announcement is for supplements to existing projects. To be eligible, the parent award must be active and the research proposed in the supplement must be accomplished within the competitive segment. The proposed supplement must be to provide for an increase in costs due to unforeseen circumstances. All additional costs must be within the scope of the peer reviewed and approved project.

IMPORTANT: The research proposed by the NIH grantee in the supplement application must be within the original scope of the NIH-supported grant project.



    Amount Description

    Application budgets are limited to direct costs of no more than $140,000.

    The funding mechanism being used to support this program, administrative supplements, can be used to cover cost increases that are associated with achieving certain new research objectives, as long as the research objectives are within the original scope of the peer reviewed and approved project, or the cost increases are for unanticipated expenses within the original scope of the project. Any cost increases need to result from making modifications to the project that would increase or preserve the overall impact of the project consistent with its originally approved objectives and purposes.

    The project and budget periods must be within the currently approved project period for the existing parent award. The parent grant must have at least 16 months of active grant support remaining from the application deadline date excluding a no cost extension. Administrative Supplement funding is for one year.  No more than one U3 administrative supplement will be awarded per grant cycle.    

    Funding Type





    Medical - Basic Science
    Medical - Clinical Science
    Medical - Translational
    Social Sciences

    External Deadline

    April 8, 2019