Resource Networks for Protein Polymorphisms in Alzheimer’s Disease and its Related Dementias (AD/ADRD) (U24 Clinical Trial Not Allowed)

Funding Agency:
National Institutes of Health

This Funding Opportunity Announcement (FOA) invites U24 Cooperative Agreement applications aiming to establish misfolded protein polymorphisms resource networks in the area of Alzheimer's disease (AD) and Alzheimer's disease-related dementias (ADRD). The central goal of these resource networks is to standardize and distribute seed, oligomers, and fibrils to other investigators in order to clarify and improve the reproducibility of experiments in AD/ADRD. Establishing standards, understanding the pathological roles of these protein polymorphs, and using newly developed analytic tools to address the direct correlation between patient-to-patient variations in Aß, α-synuclein, and tau polymorphs are the long-term goals of the resource networks supported by this FOA.


  • Letter of Intent Due Date(s):December 10, 2021
  • Application Due Date(s): Jan. 10, 2022

RFA-AG-22-030 Expiration Date January 11, 2022

Agency Website



Amount Description

Application budgets may not exceed $1 million in direct costs per year. Budgets must reflect the actual needs of the proposed project.

The maximum project period is 5 years.

    Funding Type





    Environmental & Life Sciences
    Medical - Basic Science
    Medical - Clinical Science

    External Deadline

    January 10, 2022