Revision Applications for Research on Metabolic Reprogramming to Improve Immunotherapy (P01)

Funding Agency:
National Institutes of Health

This Funding Opportunity Announcement (FOA) invites program project grant (P01) revision applications from investigators with active NIH P01 program project grant awards to support an expansion of the scope of the parent award through the addition of one or more new specific aims.  Revision applications are expected to stimulate collaborative research projects to generate a mechanistic understanding of the metabolic processes that support robust anti-tumor immune responses in vivo, determine how the metabolic landscape of the tumor microenvironment affects immune effector functions, and use this information to manipulate (or reprogram) the metabolic pathways used by the tumor, the immune response, or both to improve cancer immunotherapy.   

Deadlines:

  • Letter of Intent Due Date(s): 30 days before the due date
  • Application Due Date(s): July 10, 2014; December 11, 2014; July 10, 2015; December 11, 2015, July 11, 2016; December 14, 2016, by 5:00 PM local time of applicant organization.
  • AIDS Application Due Date(s): July 10, 2014; December 11, 2014; July 10, 2015; December 11, 2015; July 11, 2016; December 14, 2016, by 5:00 PM local time of applicant organization. 

PAR-14-086 Expiration Date December 15, 2016

Agency Website

Eligibility Requirements

The parent project must be an active NIH P01 project.  There must be two years (24 months) remaining on the project at the estimated time of award.  The PD(s)/PD(s) on the revision must be the same as the PD(s)/DI(s) on the parent grant.

Funding Type

Grant

Eligibility

Faculty

Category

Medical
Medical - Basic Science
Medical - Clinical Science
Medical - Translational

External Deadline

December 14, 2016