RUNX1 Early Career Investigator Grant

Funding Agency:
Alexs Lemonade Stand Foundation

The RUNX1 Research Program and Alex’s Lemonade Stand Foundation are delighted to continue their partnership and funding opportunity for early career investigators: the RRP and ALSF RUNX1 Early Career Investigator Program.

Key Objective: To promote the establishment of a new generation of translational and clinical researchers interested in tackling inherited hematologic malignancy predisposition disorders with a focus on RUNX1-familial platelet disorder. We believe that providing capital to early career investigators not only injects funding to where it is needed most, but also cultivates a new cohort of investigators who will be invested in an area of research that historically has had limited attention.

The RUNX1 Early Career Investigator grant is a three-year award designed to fund research investigating strategies that will lead to the development of therapies that will prevent the transition from pre-leukemia to leukemia for patients with RUNX1-FPD.

Application Due Date: December 21, 2022

Agency Website

Eligibility Requirements

• Applicants must have an M.D., Ph.D. or dual M.D., Ph.D. (D.O., MBBS or equivalent) and be within 5 years of their first faculty appointment as an Assistant Professor or equivalent. Associate and Full Professors are ineligible. If still at the Instructor level, the applicant must submit a letter of support from their mentor at the sponsoring institution. • A minimum of 75% of the applicant’s time during the award period must be allocated as protected time for all research activities. This percentage of time includes both activities on this grant and the applicant’s other research responsibilities. • Applicants may have research grants from other funding sources during the award period, but there must be clear documentation of mechanisms to avoid scientific and budgetary overlap. • Applicants must have research experience working in, and a deep understanding of, normal or malignant hematopoiesis and/or immunology. • Applicant institutions may be based in the U.S. or outside of the U.S. Applicants need not be United States citizens. Funds must be granted to non-profit institutions or organizations. • One resubmission of a previously unfunded application is allowed. Use the Resubmission section of the application to respond to the prior RRP/ALSF critique of the proposal. The response will be scored in the review process in addition to the criteria used for new applications. Resubmissions compete with new applicants for funding.



Amount Description

A RUNX1 Early Career Investigator Grant is $180,000 over 3 years (maximum $60,000 per year may be requested).

Funding Type



Junior Faculty


Medical - Clinical Science
Medical - Translational

External Deadline

December 21, 2022