Screening for Cognitive Impairment: Decision-Making (U24 Clinical Trial Optional)

Funding Agency:
National Institutes of Health

This Funding Opportunity Announcement (FOA) invites research to develop, validate, and disseminate measurement tools that could be used to screen for deficits related to decision-making, planning, and other important higher order functional outcomes in older adults. In particular, we are interested in instruments that can track changes in decision-making capacity that could be useful in the context of future screening for cognitive impairment and the development of interventions targeting functional outcomes in persons living with cognitive impairment and/or quality of life outcomes of their care partners/caregivers. The goal of this FOA is to support a research network whose goals would be to review and assess the dimensions of higher cognitive abilities and functional capacities already believed to support higher order planning and decision-making; to develop valid and reliable measures of those abilities; and to provide support for pilot efforts during the instrument development and validation in a racially, ethnically, geographically, and diagnostically diverse set of participants, as well as a set of enduring resources. Enduring resources include the measurement instruments, documentation, and normative data that will enable other, future projects to incorporate the new measurements into studies.


  • Letter of Intent Due Date(s): June 11, 2022
  • Application Due Date(s):¬†July 11, 2022

RFA-AG-23-007 Expiration Date July 12, 2022

Agency Website

Amount Description

Application budgets are limited to $1,280,000 in total costs for FY 2023; $1,760,000 in total costs for FY 2024; $2,048,000 in total costs for FY 2025; $2,816,000 in total costs for FY 2026; and $2,816,000 in total costs for FY 2027. Application budgets need to reflect the actual needs of the proposed project.

Funding Type





Medical - Basic Science
Medical - Clinical Science

External Deadline

July 11, 2022