Service-Ready Tools for Identification, Prevention, and Treatment of Individuals at Risk for Suicide (R34 Clinical Trial Optional)

Funding Agency:
National Institutes of Health

NIMH seeks applications for pilot effectiveness projects to evaluate the preliminary effectiveness of service-ready tools and technologies that can be used to advance training, quality monitoring, and quality improvement efforts and ultimately improve the availability of evidence-based suicide prevention services. Specifically, this initiative encourages research on the effectiveness-implementation continuum aimed at (1) developing and testing the effectiveness of optimized, service-ready suicide prevention tools for identification, prevention, and treatment of individuals at risk for suicide; and (2) testing strategies to improve adoption, implementation fidelity, and sustained use of these tools, guided by an implementation science framework. Given the focus on practice-ready accessible resources and products that could be readily integrated into practice, NIMH encourages the use of technology and other design features that make the tools scalable and robust against implementation drift, and a deployment-focused approach that takes into account the perspectives of key stakeholders (e.g., service users, providers, administrators) and system-level factors, such as workforce capacity that influence potential integration of tools into clinical workflows.

This Funding Opportunity Announcement (FOA) supports pilot effectiveness research to evaluate the feasibility, tolerability, acceptability, safety and preliminary indications of effectiveness of service-ready tools and technologies for suicide prevention and inform the design of definitive effectiveness trials. Support for fully-powered, definitive effectiveness studies focused on service-ready tools and technologies or suicide prevention is provided via the R01 in RFA-MH-21-110. Support for SBIR studies focused on service-ready tools and technologies or suicide prevention is provided via the R43/R44 in RFA-MH-21-112.


  • Letter of Intent Due Date(s): 30 days prior to the application due date

  • Application Due Date(s): February 18, 2021; October 15, 2021; June 15, 2022

RFA-MH-21-111 Expiration Date June 16, 2022

Agency Website



Amount Description

Direct costs are limited to $450,000 over the R34 project period, with no more than $225,000 in direct costs allowed in any single year.

The total project period may not exceed three years.

Funding Type





Engineering and Physical Sciences
Medical - Basic Science
Medical - Clinical Science
Medical - Translational

External Deadline

June 15, 2022