Shared Instrumentation for Animal Research (SIFAR) Grant Program (S10 Clinical Trial Not Allowed)

Funding Agency:
National Institutes of Health

The Shared Instrumentation for Animal Research (SIFAR) Grant Program encourages applications from groups of NIH-funded investigators to purchase or upgrade scientific instruments necessary to carry out animal experiments in all areas of biomedical research supported by the NIH. Applicants may request clusters of commercially available instruments configured as specialized integrated systems or as series of instruments to support a thematic well-defined area of research using animals or related materials. Priority will be given to uniquely configured systems to support innovative and potentially transformative investigations.

This FOA supports requests for state-of-the art commercially available technologies needed for NIH-funded research using any vertebrate and invertebrate animal species.

This funding opportunity announcement (FOA) does not support requests for single instruments. At least one item of the requested instrumentation must cost at least $50,000, after all applicable discounts. No instrument in a cluster can cost less than $20,000, after all applicable discounts. There is no maximum price requirement; however, the maximum award is $750,000.

Applicant organizations may submit more than one application, provided that each application is scientifically distinct. However, only one application per institution, as identified by DUNS, can be submitted to the SIFAR Program for any given due date.


  • Duke Internal: March 27, 2020
  • Application Due Date: June 1, 2020

PAR-20-112 Expiration Date June 2, 2020


Agency Website

Eligibility Requirements

The PD/PI chosen for this application should have documented (in the biographical sketch) technical expertise directly related to the type of the chosen instruments. The PD/PI does not need to have an NIH research grant or any other research support but is expected to be an expert on the requested instrument. The PD/PI may be a core director, tenured, or non-tenured faculty member of the applicant organization. The PD/PI must be affiliated with the applicant organization and must be registered on eRA Commons.

Multiple PDs/PIs are not allowed under the S10 mechanism.

Only one SIFAR application per institution as identified by the DUNS number, is allowed per the receipt date.
There is no restriction on the number of applications an institution can submit to the SIG and/or High-End Instrumentation (HEI) Programs each year, provided the applications request different types of equipment. Concurrent SIG, HEI and/or SIFAR applications for the same instrument (or the same type of instrument with added special accessories to meet the HEI budget requirement or the same instrument in a cluster of instruments to meet the SIFAR program requirements) are not allowed unless documentation from a high-level institutional official is provided, stating that this is not an unintended duplication, but part of a campus-wide instrumentation plan. Applicants are advised to discuss with the SIFAR Scientific/Research Contact (see Section VII) potential duplicates before submitting two applications for the same type of instrument.



      Amount Description

      Applications will be accepted for commercially available instruments only. At least one item of the requested instrumentation must cost at least $50,000, after all applicable discounts. No instrument in a cluster can cost less than $20,000, after all applicable discounts. There is no upper limit on the cost of each instrument, but the maximum award is $750,000 of direct costs. Since the cost of the various instruments will vary, it is anticipated that the amount of the award will also vary. S10 awards do not allow indirect costs.

      It is expected that applicants will employ the best economical approaches, including securing academic discounts, if applicable, to formulate a cost-effective budget while meeting the users’ scientific needs. See Section IV. 6. Funding Restrictions for additional details.

      Funding Type





      Engineering and Physical Sciences
      Environmental & Life Sciences
      Medical - Basic Science
      Medical - Clinical Science
      Medical - Translational

      Internal Nomination

      Anyone intending to submit a SIG proposal from any part of the University (Campus or Medical Center) must submit a statement of intent to OCRD by the March 27 internal deadline. This statement must include the following:

      • Requested materials:

        • NIH Biosketch from PI
        • Project Summary (30 lines of text)
        • Project Narrative (3 sentences)
        • Equipment: Describe the requested instruments by stating their manufacturers, model numbers, specific features/configurations, and accessories.

      Please submit internal materials through My Research Proposal. (Code ILN)

      Instructions for both creating an account (if you don't already have one) and submitting your materials can be found here:

      Internal Deadline

      March 27, 2020

      External Deadline

      June 1, 2020