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Sickle Pan-African Research Consortium Collaborative Sites (U01 Clinical Trial Optional)
This Funding Opportunity Announcement (FOA) seeks both applications from established sites of the Sickle Pan-African Research Consortium (SPARCO) and applications from other Sub-Saharan African nations to become the Consortium’s new sites. The renewed and expanded SPARCO including a Clinical Coordinating Center (CCC), up to three established sites and additional satellite sites, up to three new sites, and the associated Sickle Africa Data Coordinating Center (SADaCC) will together constitute the Sickle Cell Disease (SCD) in Sub-Saharan Africa (SSA) Network. This network aims at developing a sustainable resource that will advance SCD-related epidemiologic, translational, and clinical studies.
- Letter of Intent Due Date(s): May 8, 2020
- Application Due Date(s): June 8, 2020
RFA-HL-21-009 Expiration Date June 9, 2020
The established Collaborative Consortium sites refer to Non-domestic (non-U.S.) Entities (Foreign Institutions) in African countries that are already part of the Sickle Pan-African Research Consortium, specifically, 1) Ghana (Kwame Nkrumah University of Science and Technology in Kumasi), 2) Nigeria (University of Abuja in Abuja), and 3) Tanzania (Muhimbili University of Health and Allied Science, Dar es Salaam) that have each established a registry/database of at least 2,000 participants with SCD. Each established site needs to have at least one satellite site in the same country.
New Consortium sites need to be located in other Sub-Saharan Africa (SSA) countries; no application for new Consortium sites will be accepted from Ghana, Nigeria or Tanzania. Only one site will be funded for any nation.
The primary PD/PI shall have an appointment at an institution in a Sub-Saharan African (SSA) country. This affiliation shall constitute at least 75% of full time professional effort of the PD/PI in the past 2 years. For a list of countries in Sub-Saharan Africa, please refer to Sub-Saharan African Region Information provided by the Fogarty International Center of NIH. An investigator from another country cannot serve as a co-PD or co-PI but can serve as a co-investigator or consultant at the invitation of the primary PD/PI although the co-investigator or consultant cannot be compensated (i.e. with 0% effort in the budget) to ensure that all awarded funds will be used at the site and if applicable, the satellite site(s) to carry out the proposed studies.
Application budgets must not exceed direct costs of $100,000 in Fiscal Year 2021, $150,000 in Fiscal Year 2022, $150,000 in Fiscal Year 2023, and $225,000 per year in Fiscal Years 2024 and 2025. .
An application from an existing Sickle Pan-African Research Consortium site (SPARCO) that includes maintenance of an existing registry or database of SCD cases may request additional direct costs of up to $125,000 per year in Fiscal Year 2021 and additional direct costs up to $100,000 per year in Fiscal Years 2022 through 2025.