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Sleep Health Topical PCORI Funding Announcement -- Cycle 1 2024
The Patient-Centered Outcomes Research Institute (PCORI) intends to issue a Topical PCORI Funding Announcement (PFA) on January 9, 2024, seeking to fund high-quality, patient-centered comparative clinical effectiveness research (CER) projects that focus on sleep health. This preannouncement provides potential applicants additional time to identify collaborators; obtain patient and stakeholder input on potential studies; and develop responsive, high-quality proposals.
Quality sleep is an important component of health and quality of life, but over 50 million people of all ages in the United States experience sleep-related problems. This Topical PFA will solicit applications focused on sleep health. PCORI is particularly interested in applications focusing on sleep in high-need and/or underserved populations, including but not limited to shift workers, inpatients, pregnant and postpartum persons, rural populations, low-income populations, persons with intellectual and developmental disabilities, sexual/gender minorities, racial and ethnic minorities, and individuals with comorbid chronic conditions. Applications may propose comparative clinical effectiveness studies of screening, diagnostic and treatment approaches for sleep disorders (e.g., insomnia and/or obstructive sleep apnea [OSA]); interventions promoting sleep health; or system-level strategies delivered in hospital, clinic or community settings to improve patient-centered sleep outcomes.
Applications designed to develop new technology (such as mobile apps) will be considered nonresponsive. Cultural adaptation of efficacious technology-based interventions to promote sleep health equity in underserved communities may be responsive. Additionally, at least one primary outcome must be focused on improving sleep health.
Letter of Intent Deadline: Feb. 6, 2024
Areas of Interest
PCORI is particularly interested in submissions that address the following Special Areas of Emphasis (SAEs). The purpose of identifying these SAEs is to encourage submissions to these areas, not to limit submissions to these topics. Applicants addressing one of the below SAEs should identify the area that is best associated with their research approach:
Promoting Sleep Health Equity: Historically underserved and disenfranchised populations experience poorer sleep health than the general population and often lack access to adequate screening for and treatment of sleep disorders. PCORI is interested in studies comparing strategies to enhance access to efficacious screening and/or treatment for sleep disorders and to promote sleep health. Studies could include cultural tailoring as appropriate for specific populations.
Chronic Conditions Co-occurring with Sleep Disturbances: Sleep can be impacted by interventions designed to address chronic conditions co-occurring with sleep disturbances. PCORI is interested in studies of the effectiveness of interventions addressing health conditions such as obesity, mental health disorders (e.g., anxiety) and substance use disorders on the outcomes of sleep disorders (e.g., OSA and insomnia).
Focus on Sleep Health Beyond Diagnosed Sleep Disorders: Poor sleep can negatively impact physical and mental health in individuals without a diagnosed sleep disorder. PCORI is interested in studies comparing interventions designed for individuals with short or irregular sleep duration, irregular sleep-wake schedules, or otherwise disrupted sleep. Studies could focus on improving sleep health using technology-based interventions, clinical or care delivery interventions (e.g., improving provider assessment of sleep health), and/or addressing social needs with documented impact on sleep health, among other approaches.
Promoting Sleep Health in Inpatient Settings: Sleep is fundamental to recovery from acute illness, however, sleep disturbance in inpatient settings is common and contributes to worse health outcomes. PCORI is interested in studies that compare efficacious and/or widely used strategies amenable to broad implementation and adoption (e.g., sleep aids, light and manual therapies) for promoting sleep health for inpatient populations (defined broadly to include hospital and nonhospital settings) with or without a sleep disorder diagnosis.