This Small Research Grant (R03) program will support meritorious projects to provide needed scientific insight to improve the prevention, diagnosis, treatment, and/or care for individuals with Alzheimer's disease and Alzheimer's disease-related dementias (AD/ADRD). Specifically, this NOFO will support projects covering a wide range of topics related to AD/ADRD. The overall goal of this NOFO is (i) to encourage the next generation of researchers to pursue research and academic careers in AD/ADRD research; and (ii) to stimulate established researchers who have not had a major award in AD/ADRD research to perform pilot studies to develop new, innovative AD/ADRD research programs that leverage and build upon their existing expertise. Individuals from diverse backgrounds, including those from underrepresented groups are always encouraged to apply for NIH support. Investigators who have not successfully competed for an award under this or prior versions of this announcement are specifically encouraged to apply.
Application Due Date(s): Feb. 16, Jun. 16, Oct. 16
PA-25-246 Expiration Date March 17, 2026
This award is not intended for individuals with substantial experience in AD/ADRD research. Moreover, it is generally expected that applicants will not have had prior research funding as an independent PD/PI on a major NIH grant in AD/ADRD research (e.g., DP1, DP2, DP5, R01, R37, R56, RF1, RL1, U01 and R35, or serving as a PD/PI in Centers and Program Project grants). Applicants are strongly encouraged to discuss their eligibility with NIA program staff early in the application process.
Each PI is eligible to receive up to one award through this program. Recipients of awards made under PAR-23-179, PAS-19-391, PAS-19-392, PAS-19-393, and predecessors are not eligible.
Applications may request budgets of up to $100,000 in direct costs per year for up to two years.