Smoking Machine Adaptor Design Project for ENDS, Cigars, and Heated Tobacco Products (UC2) Clinical Trials Not Allowed

Funding Agency:
National Institutes of Health

FDA's CTP is seeking to develop a smoking machine adaptor for use with electronic nicotine delivery system (ENDS), cigars, and heated tobacco products that will require significant collaboration and research efforts with outside organizations.  The selected organization(s) will develop a single universal adaptor, or standardized family of adaptors, for the attachment of ENDS, cigars, and heated tobacco products to existing smoking machines originally designed for use with cigarettes and make available to tobacco stakeholders, contract and government laboratories, and academic institutions.


  • Letter of Intent Due Date(s): May 8, 2020

  • Application Due Date(s): July 10, 2020

RFA-FD-21-003 Expiration Date July 11, 2020

Agency Website

Amount Description

Application budgets need to reflect the actual needs of the proposed project and should not exceed the following in total costs (direct and indirect):

YR 01: $2,000,000

YR 02: $1,000,000

YR 03: $1,000,000

YR 04: $500,000

YR 05: $500,000

Funding Type





Engineering and Physical Sciences
Medical - Clinical Science
Medical - Translational

External Deadline

July 10, 2020