Social and Behavioral Intervention Research to Address Modifiable Risk Factors for Cancer in Rural Populations (R01 Clinical Trial Required)

Funding Agency:
National Institutes of Health

The purpose of this Funding Opportunity Announcement (FOA) is to solicit applications to develop, adapt, and test individual-, community- or multilevel interventions to address modifiable risk factors for cancer in rural populations. Applications should focus on primary prevention and assess and address one or more of the social and behavioral risk factors that contribute to cancer disparities in rural populations: tobacco use; diet, physical activity and weight; alcohol use; UV exposure; and HPV vaccination. Applications should also assess and address myriad social determinants of health, cultural factors, and health care and technology access barriers that may contribute to rural cancer disparities. This FOA also encourages implementation science research, to incorporate efficacious cancer control interventions in a coordinated way, into broader, sustainable health programs that are designed to reach rural populations and allow local customization and adaptation. 



  • Letter of Intent Due Date(s): 30 days prior to the application due date

  • Application Due Date(s): March 15, 2021; January 18, 2022

RFA-CA-20-051 Expiration Date January 19, 2022

Agency Website



Amount Description

Direct costs are limited to $700,000 per year.

The maximum project period is 5 years.

Funding Type





Community Outreach and Engagement
Medical - Basic Science
Medical - Clinical Science
Medical - Translational
Social Sciences

External Deadline

January 18, 2022