Space Biology: Animal Studies (ROSES 2021)

Funding Agency:
National Aeronautics and Space Administration

The NASA Space Biology (SB) Program falls within the Biological and Physical Sciences (BPS) Division, formerly known as the Space Life and Physical Sciences Research and Applications Division (SLSPRAD). BPS moved from the Human Exploration and Operations Mission Directorate (HEOMD) to the Science Mission Directorate (SMD) on July 20, 2020.

The program element, E.11 Space Biology: Animal Studies, specifically solicits proposals for investigations that characterize how animal respond to stressors in spaceflight or spaceflight-like environments. In general, the Space Biology Program focuses on research that element focuses on topics that will increase NASA’s understanding of how living systems respond to the unique environments that are encountered during space exploration, including the Low Earth Orbit (LEO) environment inside the International Space Station (ISS) and deep space conditions beyond LEO, including transit to and maintenance in Lunar and Martian environments.

This program element represents a collaboration between SB and the Space Radiation Element (SRE) of the Human Research Program (HRP). While studies involving animal models that will elucidate the fundamental biological changes a living system undergoes when exposed to space are of particular interest to the SB program, these studies can also provide valuable information to SRE to support the identification of translational biomarkers, characterization of disease initiation and progression, and the development of countermeasures applicable to helping astronauts thrive in both Low Earth Orbit and in deep space. SB will fund awards to investigators through this program element, while SRE will provide funded investigators proposing relevant studies access to the NASA Space Radiation Laboratory (NSRL) at Brookhaven National Laboratory for ground radiation studies.

This program element funding opportunity solicits three different Project Types: Research Investigations (RI), Early Career Investigations (ECI), and Gene Lab Analytical Investigations (GLAI) pertaining to animal and related studies. Please refer to Section 2: Scope of This Program Element, for detailed information about these project types and research emphasis solicited by this document.


  • Required Step-1 Proposals: Feb. 1, 2022
  • Step-2 Proposals: April 18, 2022




Engineering and Physical Sciences
Environmental & Life Sciences

External Deadline

February 1, 2022