Strategically Focused Research Networks: Atrial Fibrillation

Funding Agency:
American Heart Association

The American Heart Association (AHA) announces a Request for Applications for the Atrial Fibrillation Strategically Focused Research Network.

Unique to this Strategically Focused Research Network, special project funding is also available through a collaboration between the Patient-Centered Outcomes Research Institute (PCORI) and the AHA. The PCORI/AHA funding initiative seeks to use comparative effectiveness research focused on Decision-making and Choices to Inform Dialogue and Empower A-Fib Patients (DECIDE). The rationale is to enrich the overall scientific and community deliverables of the Network by testing and delivering a specific set of Shared DecisionMaking Tools to help patients with atrial fibrillation and their clinicians engage in a meaningful conversation and collectively arrive at the best individual choice for the use of oral anticoagulants. 

This Strategically Focused Research Network provides the AHA with a mechanism to enhance the understanding of the causes, biology, pathophysiology and epidemiology of Atrial Fibrillation, and to develop more effective ways to prevent and treat it with an ultimate improvement in patient outcomes. Testing effective methods for such improvement in outcomes will be provided by special funding from PCORI and the AHA. In brief, there is a large proportion of individuals with AFib who are not prescribed appropriate long-term oral anticoagulation (OAC) therapy, despite the fact that OAC is understood to reduce the risk of stroke associated with AFib by >60% [1, 2, 3]. The DECIDE Center will support the creation or adaptation of decision tools, validate them, and directly compare and evaluate shared decision-making tools and approaches in patients with atrial fibrillation and their clinicians, using comparative effectiveness research to address this important gap in evidence-based therapy.  

 An institution may submit only one AHA strategically focused research network application for any SFRN competition.


  • Duke Internal: October 30, 2017
  • Letter of Intent Deadline: Nov 30, 2017
  • Application Deadline: Jan 31, 2018

Agency Website

Amount Description

Award Amount: The maximum budget amount an AHA Center applicant may request is $3,709,200. The maximum budget amount the PCORI – AHA/ASA Collaborative: Decision-making and Choices to Inform 6 Dialogue and Empower A-Fib Patients (DECIDE) Center applicant may request is $5,000,000. The AHA reserves the right to determine the final award amount for competitive projects based on need and potential impact. 

Funding Type





Medical - Basic Science
Medical - Clinical Science
Social Sciences

Internal Nomination

Owing to the sponsor's restriction on the number of applications that may be submitted from Duke, anyone wishing to pursue nomination should submit the following materials as one PDF.

* A letter of support from dean or chair - 1 to 1.5 pages
* Brief overview of the 3 proposed projects – please label project “Basic” “Clinical” or “Population.” Include a maximum 1-2 paragraph project summary on each project along with the proposed project title.
* CV or Biosketch of project leader

Please submit internal materials through My Research Proposal. (Code ILN)

Instructions for setting up your account and uploading internal applications can be found here: Instructions_FINAL.pdf

Internal Deadline

October 30, 2017

External Deadline

January 31, 2018