Strengthening Institutional Capacity to Conduct Global Cancer Research in Low- and Middle-Income Countries (D43 Clinical Trial Not Allowed)

Funding Agency:
National Institutes of Health

The purpose of this Funding Opportunity Announcement (FOA) is to establish an institutional program for mentored training in global cancer research. This program will support research training led by the United States (U.S.)-based cancer research-intensive institutions working in collaboration with institutions in low and middle-income countries (LMICs). These training programs will be built upon the US institutions’ pre-existing training infrastructure and research collaborations with LMICs and will leverage these resources to expand the global cancer research workforce both in the US and in LMICs. The overarching goal of this initiative is to build capacity to conduct innovative and collaborative global research projects that will contribute to the advancement of basic, clinical, translational, and population-based cancer research in LMICs.

This FOA does not allow appointed trainees to lead an independent clinical trial but does allow them to obtain research experience in a clinical trial led by a mentor or co-mentor.


  • Letter of Intent Duke Date(s): 30 days prior to the application due date
  • Application Due Date(s): July 24, 2020; June 24, 2021.​​​​

RFA-CA-20-031 Expiration Date June 25, 2021

Agency Website

Eligibility Requirements

The sponsoring institution must assure support for the proposed program. Appropriate institutional commitment to the program includes the provision of adequate staff, facilities, and educational resources that can contribute to the planned program.

U.S. institutions engaged in cancer research and that meet the following criteria are eligible to apply:

  • The applicant institution should focus on basic, clinical, translational, or population-based cancer research or a combination of these programs. It is anticipated that the participating trainees would be exposed to a broad spectrum of cancer research in addition to being trained in a specific area or a combination of several cancer research areas.
  • The applicant institution should demonstrate collaborations with eligible LMIC institution(s) named in the application that is documented by joint publications, grants or previous research training activities, as well as by support letters from LMIC institutions as well as other relevant organizations in the LMIC indicating commitment to the training program.

The PD(s)/PI(s) must be an established investigator with research and training experience in the LMIC country they seek to work with.

The PD(s)/PI(s) listed in the application must be designated as the PD/PI of at least one active research award that is relevant to the research training proposed in the LMIC. The research awards may be funded by the NIH or by other national or international organizations.



        Amount Description

        Application budgets are limited to $250,000 per year (total direct costs).

         The scope of the proposed project should determine the project period. The maximum project period is 5 years.       


          Funding Type





          Curriculum Development
          International Opportunities
          Medical - Basic Science
          Medical - Clinical Science
          Medical - Translational
          Social Sciences

          External Deadline

          June 24, 2021