Studies of HIV in Digestive Diseases Limited to Gastrointestinal Mucosal Immunology and Liver Diseases (R01 Clinical Trial Optional)

Funding Agency:
National Institutes of Health

The goal of this FOA is to support innovative, basic and translational research in two areas, gastrointestinal (GI) mucosal immunology and liver disease.  The emphasis for GI mucosal immunology is on elucidation of mechanisms whereby innate and adaptive immunity in the GI tract interacts with HIV infection in the presence or absence of antiretroviral therapy (ART) and contributes to HIV infection, persistence, disruption of GI homeostasis, and pathogenesis. The emphasis for liver disease is on pathophysiologic mechanisms of injury to the liver and the biliary system during HIV infection and epidemiological studies of liver diseases and disorders in HIV patients.    


  • Letter of Intent Due Date(s): February 13, 2018
  • Application Due Date(s): March 13, 2018
  • AIDS Application Due Date(s): March 13, 2018

RFA-DK-17-038 Expiration Date March 14, 2018

Agency Website



Amount Description

Application budgets are limited to up to $500,000 direct costs, exclusive of any consortium/contractual facilities and administrative (F&A) costs, and need to reflect the actual needs of the proposed project.

Investigators may propose research projects for a maximum project period of 5 years. The scope of the proposed project should determine the project period.

    Funding Type





    Medical - Basic Science
    Medical - Clinical Science

    External Deadline

    March 13, 2018