Substance Use and Abuse, Risky Decision Making and HIV/AIDS (R01, R03, R21)

Funding Agency:
National Institutes of Health

This Funding Opportunity Announcement (FOA) is intended to stimulate model-driven research to understand the ways that people make decisions about engaging in behaviors that impact the risk of acquiring or transmitting HIV, or to adhere to treatments for HIV. Decision making processes may contribute to both substance use/abuse and other HIV acquisition or transmission risks. A better understanding of decision making processes in the context of brain neural networks and their associated functions would lead to the development of better strategies to reduce the frequency of HIV-risk behaviors. Therefore, this FOA encourages applications to study 1) cognitive, motivational or emotional mechanisms and/or 2) brain neuroendocrine and reinforcement systems that related to HIV-risk behaviors or treatment non-compliance. Interdisciplinary studies that incorporate approaches from psychology, economics, anthropology, sociology, decision sciences, neuroscience and computational modeling are encouraged. This FOA for R01 applications solicits empirical, hypothesis-driven, confirmatory research and modeling approaches. Exploratory, descriptive or hypothesis-generating research are more appropriate for the complementary FOA’s using the R21 or R03 mechanisms.  In no cases, should research involving animals be proposed.     

This FOA will utilize the R01 grant mechanism and runs in parallel with FOAs of identical scientific scope: PA-14-062, that encourages applications under the R21 mechanism, and PA-14-063, that encourages applications under the R03 mechanism.  


  • R01 Due Dates: Feb. 5, Jun. 5, Oct. 5
  • R03 and R21 Due Dates: Feb. 16, Jun. 16, Oct. 16
  • AIDS Due Dates: Jan. 7, May 7, Sep. 7

PA-14-061 Expiration Date: May 8, 2017




Engineering and Physical Sciences
Medical - Basic Science
Medical - Clinical Science
Medical - Translational
Social Sciences

External Deadline

February 5, 2017