Superfund Hazardous Substance Research and Training Program (P42 Clinical Trial Optional)

Funding Agency:
National Institutes of Health

The National Institute of Environmental Health Sciences (NIEHS) is announcing the continuation of the Superfund Hazardous Substance Research and Training Program, referred to as Superfund Research Program (SRP) Centers. SRP Center grants will support problem-based, solution-oriented research Centers that consist of multiple, integrated projects representing both the biomedical and environmental science and engineering disciplines; as well as cores tasked with administrative (which includes research translation), data management and analysis, community engagement, research experience and training coordination, and research support functions.  The scope of the SRP Centers is taken directly from the Superfund Amendments and Reauthorization Act of 1986, and includes: (1) advanced techniques for the detection, assessment, and evaluation of the effect on human health of hazardous substances; (2) methods to assess the risks to human health presented by hazardous substances; (3) methods and technologies to detect hazardous substances in the environment; and (4) basic biological, chemical, and physical methods to reduce the amount and toxicity of hazardous substances.

Only one application per institution is allowed.


  • Duke Internal: Duke is submitting a competitive renewal. Other interested applicants at Duke should contact Paul Noe ( as early as possible.
  • Letter of Intent Due Date: Jan. 15, 2021
  • Application Due Date(s): Feb. 15, 5021


RFA-ES-20-014 Expiration Date Feb. 16, 2021

Agency Website

Eligibility Requirements

Only one application per accredited institution of higher education (normally identified by having a unique DUNS number or NIH IPF number) is allowed.



Amount Description

Applications may request a budget for direct costs of up to $1.75 million dollars for the first year.

Applications may propose a project period of up to 5 years.   

Funding Type





Curriculum Development
Engineering and Physical Sciences
Environmental & Life Sciences
Medical - Basic Science
Medical - Clinical Science
Medical - Translational

Internal Nomination

Owing to the sponsor's restriction on the number of applications that may be submitted from Duke, anyone wishing to pursue nomination should submit the following materials as one PDF via the upload feature on the ORS website.

* A letter of support from dean/chair - 1 to 1.5 pages
* Project summary - 2 to 4 pages
* NIH Biosketch

The above materials should be compiled (in the order listed above) into one PDF file.
Go to Institutionally Limited Nominations/Current Open Competitions:,
Select the appropriate competition and click the Applicant button.
Follow the instructions to create a profile (if required).
Return to the funding opportunity.
Click the Applicant Button on the Opportunities page and then upload your file.
Please remember to click Submit after you upload.

External Deadline

February 15, 2021