Systems Biology-Enabled Microbiome Research to Facilitate Predictions of Interactions and Behavior in the Environment

Funding Agency:
Department of Energy

The DOE SC program in Biological and Environmental Research (BER) hereby announces its interest in receiving applications for research within the Biological System Science Division (BSSD) Genomic Science Program (GSP) ( mission-space. This FOA solicits applications for basic research that will fundamentally enhance or transform our understanding of microbial processes in terrestrial ecosystems. Of interest to the Program are interdisciplinary projects grounded in holistic, systems-level approaches to understand microbial community interactions and biogeochemical cycling. Specifically, the Program seeks to elucidate fundamental principles that advance our understanding of regulatory, metabolic, and signaling networks among microbes, in microbe-plant interactions, the cycling and long-term storage or sequestration of carbon in soils, and the biogeochemical conversion of other elements, including nutrients, particularly as they relate to rapidly changing environmental conditions.


  • Required Pre-Application: Jan. 14, 2022
  • Full Application: April 4, 2022

Agency Website

Eligibility Requirements

Applicant institutions are limited to no more than one pre-application or applications for each PI at the applicant institution. DOE will consider the latest received submissions to be the institution’s intended submissions.

Amount Description

Ceiling $1,200,000 per year

Floor $250,000 per year

DOE anticipates making awards with a project period of three years.

Funding Type





Environmental & Life Sciences

External Deadline

January 14, 2022