Tailoring Interventions to Improve Preventive Health Service Use (R61/R33 Clinical Trial Required)

Funding Agency:
National Institutes of Health

This Funding Opportunity Announcement (FOA) invites R61/R33 applications to develop interventions for physician compliance with recommended prevention guidelines for older adults from the Centers for Disease Control and Prevention (CDC) and the US Preventive Services Task Force (USPTF). Specifically, applicants will develop electronic health record (EHR)-based interventions to improve quality of care and health outcomes and reduce health disparities. This FOA will support an R61 pilot phase, which will allow researchers to use data analytics tools, including machine learning approaches, to establish the feasibility of identifying groups of patients not receiving recommended preventive care, and then create scalable, tailored interventions for these groups to help overcome barriers to uptake. If successful, researchers may transition to an R33 phase for implementation of pragmatic trials. All applicants are required to address health disparities.

The transition from the R61 to the R33 phase of the award will be administratively reviewed for successful completion of the go/no-go criteria specified for the R61 phase.


  • Letter of Intent Due Date(s): September 28, 2019
  • Application Due Date(s): October 28, 2019

RFA-AG-20-045 Expiration Date October 29, 2019

Agency Website

Amount Description

For the R61 planning phase, the combined budget for direct costs for the two-year project period may not exceed $400,000, with no more than $200,000 requested in any single year.

For the three-year R33 implementation phase, applicants' combined budget for direct costs may not exceed $1,350,000. Applicant's budgets need to reflect the actual needs of the proposed project.

Funding Type





Medical - Clinical Science
Medical - Translational

External Deadline

October 28, 2019