Tobacco Regulatory Science Small Grant Program for New Investigators (R03)

Funding Agency:
National Institutes of Health

The purpose of this Funding Opportunity Announcement (FOA) is to support New Investigators in the biomedical, behavioral, and social sciences who are in the early stages of establishing independent careers in tobacco regulatory research.  The R03 grant mechanism supports different types of projects including pilot and feasibility studies; secondary analysis of existing data; small, self-contained research projects; development of research methodology; and development of new research technology.  Applicants are encouraged to conduct projects that ultimately have potential to inform regulations on tobacco product manufacturing, distribution, and marketing.  Research projects must address the research priorities related to the regulatory authority of the Food and Drug Administration (FDA) Center for Tobacco Products (CTP) as mandated by the Family Smoking Prevention and Tobacco Control Act (FSPTCA), Public Law 111-31.

The awards under this FOA will be administered by NIH using designated funds from the FDA CTP for tobacco regulatory science. Research findings generated from this FOA are expected to provide sufficient preliminary data for subsequent investigator-initiated research that is relevant to the FDA's regulation of the manufacture, distribution, and marketing of tobacco products to protect public health.  The NIH and the FDA have formed an interagency partnership to foster research relevant to tobacco regulatory science within the framework of the FSPTCA.

Deadlines:

  • Letter of Intent Due Date(s): June 29, 2015, January 4, 2016, June 30, 2016, January 5, 2017
  • Application Due Date(s): August 20, 2015, February 23, 2016, July 20, 2016, February 23, 2017, by 5:00 PM local time of applicant organization

RFA-OD-15-004 Expiration Date February 24, 2017

Agency Website

Areas of Interest

This FOA is focused on the following ten FDA CTP interest areas. Only applications proposing research projects/pilots relevant to one or more of these ten areas will be considered for funding.

1. Nicotine dependence threshold among youth and adults and impact of nicotine reduction on tobacco product use behavior (e.g., topography, compensation, switching, multiple use, initiation, cessation, relapse)

2. Cigar (small, large, cigarillos) initiation, use (including transitions to other tobacco products and multiple use), perceptions, dependence and toxicity

3. Smokeless tobacco initiation, use (including transitions to other tobacco products and multiple use), perceptions, dependence and toxicity

4. E-cigarettes initiation, use (including transitions to other tobacco products and multiple use), perceptions, dependence, toxicity

5. Other tobacco product (e.g., hookah, pipes, dissolvables) initiation, use (including transitions to other tobacco products and multiple use), perceptions, dependence, toxicity

6. The impact of tobacco product characteristics, (e.g., ingredients, constituents, components, additives such as flavors, and labeling and marketing) on initiation, especially among youth and other vulnerable populations

7. Toxicity thresholds for each of the 20 harmful and potentially harmful constituents identified in the March 2012 Guidance for Industry http://www.fda.gov/TobaccoProducts/GuidanceComplianceRegulatoryInformation/ucm297752.htm

8. Computational/mathematical modeling and simulation and/or statistical modeling of the public health impact of FDA/CTP regulation of potential modified risk tobacco products, e.g., product standards, communications regarding risks of tobacco products

9. Consumer perceptions of tobacco products including the impact of labeling and marketing

10. Effective communication strategies regarding  harmful and potentially harmful constituents and risks of tobacco products

Eligibility Requirements

Only New Investigators who fit the criteria in this section are eligible to apply to this FOA.

Amount

$150,000

Amount Description

Application budgets are limited to $75,000 in direct costs per year.

Grants awarded to this FOA will be up to two years in length.

Funding Type

Grant

Eligibility

Junior Faculty

Category

Engineering and Physical Sciences
Medical
Medical - Basic Science
Medical - Clinical Science
Medical - Translational

External Deadline

February 23, 2017