Translating Duke Health Request for Ideas in Cardiovascular Health [Duke Internal Funding -- for Duke Faculty only]

Funding Agency:
Duke University

The Translating Duke Health Cardiovascular Disease Initiative is pleased to announce a call for proposals to identify areas for investment that will accelerate research in the area of Cardiovascular Resistance, Resilience and Rejuvenation.  Our goal is to build on existing Duke expertise and resources to create a small number of research ‘force multipliers’ or platforms for multidisciplinary work addressing important areas of unmet needs.  We are looking for proposals across the continuum of bench to bedside to population health. Successful ideas will greatly enhance our environment for discovery and will have potential for both scientific and public health impact.

We are interested in identifying ‘health protection’ factors (vs risk factors), pathways and mechanisms that preserve or restore health, their mechanisms of benefit, and how they may be harnessed to yield testable interventions promoting CV health. Priority areas of focus are:

  • Defining and achieving cardiometabolic health over the life span
  • Resisting and repairing vascular injury
  • Reestablishing normal myocardial and ventricular functioning

This is a multi-stage process. At this time we are looking for Letters Of Intent (LOI) describing ideas regarding possible projects. Selected LOIs will be invited to submit a formal application including information about the concept, feasibility, impact, and strategies for future funding to the TDH CV Steering Committee. Finally, top finalists will defend their proposals verbally to the TDH CV Scientific Oversight Committee for final selection. We plan to make up to three high impact investments ranging from $1-3 Million.

Deadline: Aug. 1, 2018




Engineering and Physical Sciences
Environmental & Life Sciences
Medical - Basic Science
Medical - Clinical Science
Medical - Translational
Social Sciences

External Deadline

August 1, 2018