Sponsor Deadline
Posted: 1/3/2023

Translational Centers for Microphysiological Systems (TraCe MPS) (U2C Clinical Trials Not Allowed)

The purpose of this funding opportunity announcement (FOA) is to establish Centers to support research that will accelerate the translational use of Microphysiological Systems (MPS) in drug development through regulatory acceptance and adoption for industrial use, by establishing MPS that are fit-for-purpose for industry needs and have specific defined contexts of use (CoUs) and will be developed with consideration of applicable expectations to achieve regulatory approval. For this FOA, the term “drugs” refers to both human pharmacological and biological products unless otherwise specified. These Centers will further the development of MPS as drug development tools (DDTs) that, once qualified, will be made publicly and commercially available to fill unmet needs in drug development.


  • Letter of Intent Due Date(s): 30 days before the application due date

  • Application Due Date: March 27, 2023

RFA-TR-23-001 Expiration Date March 28, 2023

Funding Type