Pfizer Global Medical Grants (GMG) supports the global healthcare community’s independent initiatives (e.g., research, quality improvement, or education) to improve patient outcomes in areas of unmet medical need that are aligned with Pfizer’s medical and/or scientific strategies. Pfizer’s GMG competitive grant program involves a publicly posted general Request for Proposal (RFP) that provides detail regarding a general area of interest, sets timelines for review and approval, and uses an internal Pfizer review process to make final grant decisions. Organizations are invited to submit an application addressing the research gaps as outlined in the specific RFP.
Research projects that will be considered for support include:
• Early identification, evaluation, diagnosis, prognosis & treatment
• Natural history
• Epidemiology o Prevalence of TTR amyloidosis among at-risk populations (e.g. carpal tunnel syndrome, aortic stenosis, hypertrophic cardiomyopathy, lumbar spinal stenosis, hip & knee arthroplasty, atrial fibrillation) o Changing epidemiology of cardiac amyloid subtypes (hereditary vs wild-type)
• Scintigraphy o Use of scintigraphy for diagnosis of early disease and/or monitoring disease progression o Phenotype and management of patients with Perugini Grade 1 uptake
• New methodology to accelerate appropriate ATTR CM patient identification including Machine learning/ Artificial Intelligence and new biomarkers
• Study of hereditary ATTR genotypes and phenotypes o Non-Val30Met genotypes o Val122Ile, Thr60Ala, Val30Met, and others
• Mixed phenotypic manifestations (e.g. polyneuropathy and cardiomyopathy)
• Use of tafamidis in the clinical setting (i.e. real world evidence)
Grant Application due date: May 5, 2022
Geographic Scope: United States
• The institution and principal investigator (PI) must be based in one of the eligible countries noted above. • Only organizations are eligible to receive grants, not individuals or medical practice groups. • The applicant (PI) must have a medical or postdoctoral degree (MD, PhD, or equivalent), an advanced nursing degree (BSN with a MS/PhD), or a degree in Pharmacy, Physiotherapy, or Social Work. • Applicant must be affiliated with a host institution
Individual projects requesting up to $75,000 will be considered.