Tropical Medicine Research Centers (U01 Clinical Trial Not Allowed)

Funding Agency:
National Institutes of Health

This funding opportunity announcement (FOA) solicits research applications focused on the etiology, epidemiology, pathogenesis, clinical manifestations, diagnosis, prevention, treatment and control of select Neglected Tropical Diseases (NTDs) in endemic areas. The Tropical Medicine Research Centers (TMRCs) are intended to advance NIAID’s global research effort by targeting research endeavors to: develop novel diagnostic, prevention and therapeutic strategies adapted for the unique needs of low and middle-income countries (LMICs), as classified by the World Bank; create and sustain in-country research capacity; stimulate scientific collaboration and global partnerships; provide opportunities for junior and early-stage investigators to conduct research on NTDs; and facilitate sample sharing to support translational research to develop or evaluate new drugs, diagnostics, vaccines, therapeutics, and/or vector control strategies.


  • Letter of Intent Due Date(s): 30 days prior to the application due date

  • Application: June 18, 2021

RFA-AI-21-004 Expiration Date June 19, 2021

Agency Website

Amount Description

Application budgets should not exceed $500,000 per year in direct costs. It is required that at least 65% of the annual direct costs should be committed for field work and related research activities at the endemic sites. Awards are contingent upon the availability of funds and submission of a sufficient number of meritorious applications.

The scope of the proposed project should determine the project period. The maximum period is 5 years.

Funding Type





International Opportunities
Medical - Basic Science
Medical - Clinical Science

External Deadline

June 18, 2021