UA6 Life Course Intervention Research Network (LCI-RN)

Funding Agency:
Health Resources and Services Administration

This notice solicits applications for the Life Course Intervention Research Network (LCIRN) Program. The life course theory posits that multiple determinants, such as health care, nutrition, stress, community/family supports, and environmental exposures, operating over the life course, are critical drivers of maternal and child health (MCH) outcomes. 

The purpose of this program is to coordinate a national platform to support research studies to advance knowledge in disease prevention and health promotion across the life course by supporting a national network of interdisciplinary MCH researchers to design, plan, and implement multi-site life course intervention research studies. 

The LCI-RN is designed to accelerate the translation of the life course theory to MCH practice and policy, and foster its rapid adoption into clinical and public health settings through rigorous testing, systems integration, and collaboration among entities interested in improving MCH outcomes. 

The cooperative agreement will establish and maintain an interdisciplinary, multi-site, collaborative Research Network (hereafter referred to as “the Network”). The Network will lead, promote, and coordinate national research activities to advance and strengthen the evidence base related to disease prevention and health promotion through an improved understanding of risk factors across the life course. The Network infrastructure will support the design of a portfolio of multi-site, interdisciplinary research that focuses on fostering the implementation of multi-site intervention research studies, translation of research to policy and practice, and provision of a mentoring environment to train a new generation of clinical and non-clinical researchers in applied and translational research, drawing upon life course theory and science. The Network should incorporate the HRSA clinical priorities that are relevant to life-course and aligned with Title V Maternal and Child Health Block Grant national performance measures including opioid and other substance abuse, mental health, and/or childhood obesity as part of its overall research strategy and study plan.

Deadline: June 12, 2018


Agency Website

Eligibility Requirements

Domestic public or non-profit institutions of higher learning and public or private nonprofit agencies engaged in research or in programs relating to maternal and child health and/or services for children with special health care needs are eligible to apply. See 42 CFR § 51a.3(b). Domestic faith-based and community-based organizations, tribes, and tribal organizations are eligible to apply, if they otherwise meet these eligibility criteria. 



Amount Description

HRSA expects approximately $1,200,000 to be available annually to fund one recipient. You may apply for a ceiling amount of up to $1,200,000 total cost (including both direct and indirect, facilities, and administrative costs) per year. The period of performance is September 1, 2018 through August 31, 2023 (5 years). Funding beyond the first year is dependent on the availability of appropriated funds for “Life Course Intervention Research Network Program” in subsequent fiscal years, satisfactory recipient performance, and a decision that continued funding is in the best interest of the Federal Government.

Funding Type





Curriculum Development
Medical - Basic Science
Medical - Clinical Science

External Deadline

June 12, 2018