Understanding Senescence in Brain Aging and Alzheimer's Disease (R01 Clinical Trial Not Allowed)

Funding Agency:
National Institutes of Health

The goal of this Funding Opportunity Announcement (FOA) is to support research focused on understanding the role of senescence in brain aging and in Alzheimer's disease (AD). This FOA encourages research projects addressing critical knowledge gaps in our understanding of the neurobiology of senescence through cutting-edge techniques, cross-disciplinary collaborations, and/or conceptual innovation, leveraging what is known about senescence in peripheral tissues to learn more about brain aging. Developing a clear understanding of the mechanisms driving aging processes in the brain, including senescence, is essential for combating age-related neurodegenerative diseases.


  • Letter of Intent Due Date(s): September 17, 2019
  • Application Due Date(s): October 17, 2019

RFA-AG-20-025 Expiration Date: October 18, 2019

Agency Website



Amount Description

Application budgets are limited to $250,000 in direct costs.

The scope of the proposed project should determine the project period. The maximum project period is 5 years.

Funding Type





Environmental & Life Sciences
Medical - Basic Science
Medical - Clinical Science

External Deadline

October 17, 2019