Urgent Competitive Revision to Existing NIH Grants and Cooperative Agreements (Urgent Supplement - Clinical Trial Optional)

Funding Agency:
National Institutes of Health

 The National Institutes of Health (NIH) hereby notify Principal Investigators on specific types of NIH research grants, listed in the Urgent Notice of Special Interest that funds may be available for competitive revisions to meet immediate needs to help address a specific public health crisis in a timely manner, but that were unforeseen when the new or renewal application or grant progress report for non-competing continuation support was submitted.  Applications for Urgent Competitive Revisions will be routed directly to the NIH awarding component listed on the NoA of the most recent parent award.

Only applications submitted in response to an Urgent Guide Notice published by an IC will be allowed to apply to this FOA.    

Earliest start dates may vary by awarding IC.  See the Urgent Guide Notices for any applicable Application Due Dates. 

Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

PA-23-044 Expiration Date October 26, 2025

Agency Website

Eligibility Requirements

All organizations administering an eligible parent award may apply for a supplement under this announcement.

For supplements to parent awards that include multiple PDs/PIs, the supplement may be requested by any or all of the PDs/PIs (in accordance with the existing leadership plan) and submitted by the awardee institution of the parent award. Do not use this administrative supplement application to add, delete, or change the PDs/PIs listed on the parent award. Visit the Multiple Program Director/Principal Investigator Policy in the SF424 (R&R) Application Guide for more information.

Applicant organizations may submit more than one application, provided that each is sufficiently distinct from any other administrative supplement currently under consideration by the awarding NIH Institute or Center.

Funding Type





Medical - Basic Science
Medical - Clinical Science
Medical - Translational

External Deadline

October 25, 2025