Using Human Cell Animal Chimera Brains to Study HIV Latency and Pathology R01 - Clinical Trials Not Allowed

Funding Agency:
National Institutes of Health


This Funding Opportunity Announcement (FOA) invites applications for pre-clinical and translational research using human cell-mice chimera animals to study HIV pathology in functional live brain environments, with the presence of abused substances. Research awards are expected to support replicable mechanistic studies that enable the advancement of translational development for the interventions and treatments of HIV-associated neurological disorders (HAND) and for the eventual eradication of HIV from brain cells containing HIV provirus.


  • Letter of Intent Due Date(s): October 13, 2020

  • Application Due Date(s): November 13, 2020

  • AIDS Application Due Date(s): November 13, 2020

RFA-DA-21-026 Expiration Date November 14, 2020

Agency Website



Amount Description

Application budgets are limited to no more than $500,000 direct cost.

The maximum project period is 5 years.

Funding Type





Medical - Clinical Science
Medical - Translational

External Deadline

November 13, 2020