V Clinical Scholar Grants

Funding Agency:
V Foundation

To accelerate cancer treatment and cures, the V Foundation proposes to develop the careers of clinicians who will become leaders in developing programs of clinical trials that are sequential and based on hypothesis–driven research. The competitive candidate will have a thorough knowledge of clinical trials and cancer biology as well as the ability to utilize new research discoveries for clinical intervention, the ability to develop a long-term plan to cure different forms of cancer, communicate with government agencies, and collaborate with the biotechnology and pharmaceutical industry to facilitate progress in clinical care. Clinical Scholars will be expected to lead a program of hypothesis-driven clinical trials, initiating and completing multiple projects mentored by a clinical and laboratory mentors who have a track record for conducting hypothesis-driven research with a strong translational component, often in collaboration with investigators from other disciplines. Each awardee will be expected to conduct the initial clinical trials in their designed program during the two years of the award. Trials will be based on novel pre-clinical data. Each hypothesis-driven clinical trial will include laboratory correlates that will inform the design of subsequent trials. Candidates will become familiar with the methodology, potential and limitations of laboratory correlates. Note: This program is distinct from the pre-existing V Scholar program which is for early investigators of all types (PhD, DVM and/or MD), many of which are not engaged in clinical research.

The Duke Cancer Institute has been invited by The V Foundation to participate in their 2020 V Foundation Call for V Clinical Scholar grant proposals.  This call for applications is specifically to support a clinician who can develop a program of clinical trials.

The DCI is invited to submit one nominee, therefore we will be conducting an internal review of applications. The following items are required and will be reviewed by the DCI’s Scientific Review Committee.

  • Two (2) page summary including the following information:

    • Brief statement of applicant’s eligibility
    • Title of the proposed research project
    • Brief description of the research proposal
  • Budget and budget justification
  • Applicant’s NIH Biosketch

 

Applications for internal review are due to Daven Ria (daven.ria@duke.edu) no later than 5:00pm by Wednesday, February 26th (please send your application in one PDF).  Selected nominees will be notified by Monday, March 9th.  The nomination form (to be submitted to V Foundation by the DCI) is due March 16, 2020.

This funding opportunity is open to DCI members only.

Agency Website

Eligibility Requirements

Only NCI-Designated Comprehensive Cancer Centers receiving this RFA are eligible to nominate an applicant. Centers must be able to demonstrate that they have the capacity to develop a training program/mentorship for these clinical scholars. Within an institution, applicants must be clinicians (at minimum, Assistant Professor for at least three years) and have had experience in leading clinical trials, but have not yet achieved the level of Full Professor. Applicants must be board-certified (if applicable to their discipline; certification received within previous 7 years) or board-eligible in (for example, but not limited to) surgical oncology, gynecologic oncology, medical oncology, radiation oncology, pediatric oncology, or internal medicine. Other oncology disciplines that are not listed may also be included and in some cases may not require board certification, depending on discipline. The Department Chair and Division Head must support the applicant’s plans for career development and commit to long-term support of the applicant.

Amount

$200,000

Amount Description

This is a $200,000 grant paid over two years, and does not cover indirect costs. A progress report and financial expenditure report are due annually. This grant will allow flexibility in how the PI can use these funds (e.g., salary, protected time, program costs and some correlates) but is insufficient to fund the major costs of a clinical trial.

Funding Type

Grant

Eligibility

Faculty

Category

Medical
Medical - Basic Science
Medical - Clinical Science
Medical - Translational

Internal Deadline

February 26, 2020

External Deadline

March 16, 2020